Characterizing Vaccine-associated Risks Using Cubic Smoothing Splines
نویسندگان
چکیده
منابع مشابه
Characterizing vaccine-associated risks using cubic smoothing splines.
Estimating risks associated with the use of childhood vaccines is challenging. The authors propose a new approach for studying short-term vaccine-related risks. The method uses a cubic smoothing spline to flexibly estimate the daily risk of an event after vaccination. The predicted incidence rates from the spline regression are then compared with the expected rates under a log-linear trend that...
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ژورنال
عنوان ژورنال: American Journal of Epidemiology
سال: 2012
ISSN: 0002-9262,1476-6256
DOI: 10.1093/aje/kws158